Anti-CTNND2 Antibody
Catalog No : IGX-44253
262.00€
188.00€
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| Description | Has a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses (PMID:25807484). Involved in the regulation of Wnt signaling (PMID:25807484). It probably acts on beta-catenin turnover, facilitating beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation . Functions as a transcriptional activator when bound to ZBTB33 . May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules. | ||
|---|---|---|---|
| Other names | Catenin delta-2, Delta-catenin, GT24, Neural plakophilin-related ARM-repeat protein, NPRAP, Neurojungin, CTNND2, NPRAP | ||
| Cellular localization | Nucleus, Adherens Junction, Dendrite, Perikaryon | ||
| Research area | Neuroscience | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9UQB3 | ||
| Product name | Anti-CTNND2 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44253 | ||
| Supplier’s Catalog No | IGX-44253 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Catenin delta-2 protein (4-308AA) | ||
| Specificity | CTNND2 antibody detects endogenous level of CTNND2 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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