Anti-C2CD3 Antibody
Catalog No : IGX-44322
262.00€
188.00€
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| Description | Component of the centrioles that acts as a positive regulator of centriole elongation (PMID:24997988). Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation (PMID:23769972). Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3. | ||
|---|---|---|---|
| Other names | C2 domain-containing protein 3, C2CD3 | ||
| Cellular localization | Cilium Basal Body, Centriole | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q4AC94 | ||
| Product name | Anti-C2CD3 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44322 | ||
| Supplier’s Catalog No | IGX-44322 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human C2 domain-containing protein 3 protein (2079-2265AA) | ||
| Specificity | C2CD3 antibody detects endogenous level of C2CD3 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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