Anti-BANF1 Antibody
Catalog No : IGX-44409
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. (Microbial infection) Exploited by retroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. (Microbial infection) In case of poxvirus infection, has an antiviral activity by blocking viral DNA replication. | ||
|---|---|---|---|
| Other names | Barrier-to-autointegration factor, Breakpoint cluster region protein 1, [Cleaved into: Barrier-to-autointegration factor, N-terminally processed], BANF1, BAF BCRG1 | ||
| Cellular localization | Nucleus, Nucleus Envelope, Chromosome, Cytoplasm | ||
| Research area | Microbiology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | O75531 | ||
| Product name | Anti-BANF1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44409 | ||
| Supplier’s Catalog No | IGX-44409 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Barrier-to-autointegration factor protein (2-89AA) | ||
| Specificity | BANF1 antibody detects endogenous level of BANF1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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