Anti-KCNC1 / Kv4 Antibody
Catalog No : IGX-44423
262.00€
188.00€
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| Description | Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient (PMID:25401298). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well. Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons. | ||
|---|---|---|---|
| Other names | Potassium voltage-gated channel subfamily C member 1, NGK2, Voltage-gated potassium channel subunit Kv3.1, Voltage-gated potassium channel subunit Kv4, KCNC1 | ||
| Cellular localization | Membrane, Multi-Pass Membrane, Presynaptic Membrane, Axon | ||
| Research area | Neuroscience | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P48547 | ||
| Product name | Anti-KCNC1 / Kv4 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44423 | ||
| Supplier’s Catalog No | IGX-44423 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Potassium voltage-gated channel subfamily C member 1 protein (1-190AA) | ||
| Specificity | KCNC1 antibody detects endogenous level of KCNC1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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