Anti-KCNJ3 / Inward rectifier K channel Kir3.1 Antibody
Catalog No : IGX-44424
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat. | ||
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| Other names | G protein-activated inward rectifier potassium channel 1, GIRK-1, Inward rectifier K,+, channel Kir3.1, Potassium channel, inwardly rectifying subfamily J member 3, KCNJ3, GIRK1 | ||
| Cellular localization | Membrane, Multi-Pass Membrane | ||
| Research area | Neuroscience | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P48549 | ||
| Product name | Anti-KCNJ3 / Inward rectifier K channel Kir3.1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44424 | ||
| Supplier’s Catalog No | IGX-44424 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human G protein-activated inward rectifier potassium channel 1 protein (350-487AA) | ||
| Specificity | KCNJ3 antibody detects endogenous level of KCNJ3 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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