Anti-DLG1 Antibody
Catalog No : IGX-44531
262.00€
188.00€
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| Description | Essential multidomain scaffolding protein required for normal development . Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel. During long-term depression in hippocampal neurons, it recruits ADAM10 to the plasma membrane (PMID:23676497). | ||
|---|---|---|---|
| Other names | Disks large homolog 1, Synapse-associated protein 97, SAP-97, SAP97, hDlg, DLG1 | ||
| Cellular localization | Plasma Membrane, Basolateral Membrane, Sarcolemma, Apical Membrane, Endoplasmic Reticulum Membrane, Membrane, Peripheral Membrane, Postsynaptic Density, Synapse, Cell Junction, Cytoplasm | ||
| Research area | Neuroscience | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q12959 | ||
| Product name | Anti-DLG1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44531 | ||
| Supplier’s Catalog No | IGX-44531 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Disks large homolog 1 protein (662-773AA) | ||
| Specificity | DLG1 antibody detects endogenous level of DLG1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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