Anti-PCID2 Antibody
Catalog No : IGX-44537
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation . As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (PMID:22307388) (Probable). Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells (PMID:24896180). | ||
|---|---|---|---|
| Other names | PCI domain-containing protein 2, CSN12-like protein, PCID2 | ||
| Cellular localization | Cytoplasm, Nuclear Pore Complex, Nucleus | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q5JVF3 | ||
| Product name | Anti-PCID2 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44537 | ||
| Supplier’s Catalog No | IGX-44537 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human PCI domain-containing protein 2 protein (2-250AA) | ||
| Specificity | PCID2 antibody detects endogenous level of PCID2 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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