Anti-SLC25A1 Antibody

Catalog No : IGX-44570
262.00€
188.00€

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Description Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate (PMID:29031613, PMID:29238895). Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis- but not trans-aconitate and to a lesser extend maleate and succinate (PMID:29031613). Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD+ for the glycolytic pathway. Required for proper neuromuscular junction formation (Probable).
Other names Tricarboxylate transport protein, mitochondrial, Citrate transport protein, CTP, Solute carrier family 25 member 1, Tricarboxylate carrier protein, SLC25A1, SLC20A3
Cellular localization Mitochondrion Inner Membrane, Multi-Pass Membrane
Research area Signal Transduction
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P53007
Product name Anti-SLC25A1 Antibody
Catalog No IGX-44570
Supplier’s Catalog No IGX-44570
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:20-1:200, IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Tricarboxylate transport protein, mitochondrial protein (144-182AA)
Specificity SLC25A1 antibody detects endogenous level of SLC25A1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).