Anti-MAP3K11 Antibody
Catalog No : IGX-44641
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle. | ||
|---|---|---|---|
| Other names | Mitogen-activated protein kinase kinase kinase 11, EC 2.7.11.25, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase, MAP3K11, MLK3 PTK1 SPRK | ||
| Cellular localization | Cytoskeleton, Centrosome | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q16584 | ||
| Product name | Anti-MAP3K11 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44641 | ||
| Supplier’s Catalog No | IGX-44641 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Mitogen-activated protein kinase kinase kinase 11 protein (536-693AA) | ||
| Specificity | MAP3K11 antibody detects endogenous level of MAP3K11 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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