Anti-ROR2 Antibody

Catalog No : IGX-44650
262.00€
188.00€

Shipping cost plus VAT not included , delivery in 7-14 business days

Description Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development . Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PMID:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PMID:25029443).
Other names Tyrosine-protein kinase transmembrane receptor ROR2, EC 2.7.10.1, Neurotrophic tyrosine kinase, receptor-related 2, ROR2, NTRKR2
Cellular localization Membrane, Single-Pass Type I Membrane
Research area Signal Transduction
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q01974
Product name Anti-ROR2 Antibody
Catalog No IGX-44650
Supplier’s Catalog No IGX-44650
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:20-1:200, IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Tyrosine-protein kinase transmembrane receptor ROR2 protein (752-926AA)
Specificity ROR2 antibody detects endogenous level of ROR2 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).