Anti-SREBF2 Antibody
Catalog No : IGX-44655
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway . Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes. | ||
|---|---|---|---|
| Other names | Sterol regulatory element-binding protein 2, SREBP-2, Class D basic helix-loop-helix protein 2, bHLHd2, Sterol regulatory element-binding transcription factor 2, [Cleaved into: Processed sterol regulatory element-binding protein 2], SREBF2, BHLHD2 SREBP2 | ||
| Cellular localization | Golgi Apparatus Membrane, Multi-Pass Membrane, Endoplasmic Reticulum Membrane, Copii-Coated Vesicle Membrane, Nucleus | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q12772 | ||
| Product name | Anti-SREBF2 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44655 | ||
| Supplier’s Catalog No | IGX-44655 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Sterol regulatory element-binding protein 2 protein (75-164AA) | ||
| Specificity | SREBF2 antibody detects endogenous level of SREBF2 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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