Anti-TRABD2B Antibody
Catalog No : IGX-44746
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation. | ||
|---|---|---|---|
| Other names | Metalloprotease TIKI2, EC 3.4.-.-, Heart, kidney and adipose-enriched transmembrane protein homolog, TRAB domain-containing protein 2B, TRABD2B, HKAT TIKI2 | ||
| Cellular localization | Membrane, Single-Pass Type I Membrane | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | A6NFA1 | ||
| Product name | Anti-TRABD2B Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44746 | ||
| Supplier’s Catalog No | IGX-44746 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Metalloprotease TIKI2 protein (195-405AA) | ||
| Specificity | TRABD2B antibody detects endogenous level of TRABD2B protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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