Anti-CAPRIN2 Antibody
Catalog No : IGX-44749
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway (PMID:18762581). Facilitates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling (PMID:27821587). May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons . Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation (PMID:14593112). May be involved in apoptosis (PMID:14593112). | ||
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| Other names | Caprin-2, C1q domain-containing protein 1, Cytoplasmic activation/proliferation-associated protein 2, Gastric cancer multidrug resistance-associated protein, Protein EEG-1, RNA granule protein 140, CAPRIN2, C1QDC1 EEG1 KIAA1873 RNG140 | ||
| Cellular localization | Cytoplasm, Mitochondrion, Membrane, Peripheral Membrane | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q6IMN6 | ||
| Product name | Anti-CAPRIN2 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44749 | ||
| Supplier’s Catalog No | IGX-44749 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Peptide sequence from Human Caprin-2 protein (83-100AA) | ||
| Specificity | CAPRIN2 antibody detects endogenous level of CAPRIN2 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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