Anti-DTX3 Antibody

Catalog No : IGX-44750
262.00€
188.00€

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Description Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context . Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Other names Probable E3 ubiquitin-protein ligase DTX3, EC 2.3.2.27, Protein deltex-3, Deltex3, RING finger protein 154, RING-type E3 ubiquitin transferase DTX3, DTX3, RNF154
Cellular localization Cytoplasm
Research area Epigenetics & Nuclear Signaling
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q8N9I9
Product name Anti-DTX3 Antibody
Catalog No IGX-44750
Supplier’s Catalog No IGX-44750
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:20-1:200, IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Probable E3 ubiquitin-protein ligase DTX3 protein (90-347AA)
Specificity DTX3 antibody detects endogenous level of DTX3 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).