Anti-PAEP Antibody
Catalog No : IGX-44836
262.00€
188.00€
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| Description | Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities (PMID:9918684, PMID:7531163). Glycodelin-C stimulates binding of spermatozoa to the zona pellucida (PMID:17192260). Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa (PMID:12672671). Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa (PMID:15883155). | ||
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| Other names | Glycodelin, GD, Placental protein 14, PP14, Pregnancy-associated endometrial alpha-2 globulin, PAEG, PEG, Progestagen-associated endometrial protein, Progesterone-associated endometrial protein, Zona-binding inhibitory factor-1, ZIF-1, PAEP | ||
| Cellular localization | Secreted | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P09466 | ||
| Product name | Anti-PAEP Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44836 | ||
| Supplier’s Catalog No | IGX-44836 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IP | ||
| Recommended dilutions | IHC: 1:20-1:200, IP: 1:200-1:2000 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Glycodelin protein (19-180AA) | ||
| Specificity | PAEP antibody detects endogenous level of PAEP protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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