Anti-SETD3 Antibody

Catalog No : IGX-44956
262.00€
188.00€

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Description Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73' (PMID:30526847, PMID:30626964, PMID:30785395). Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery (PMID:30626964). Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin (PMID:30626964, PMID:30785395).
Other names Histone-lysine N-methyltransferase setd3, EC 2.1.1.43, SET domain-containing protein 3, SETD3, C14orf154
Cellular localization Cytoplasm, Nucleus
Research area Cell Biology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q86TU7
Product name Anti-SETD3 Antibody
Catalog No IGX-44956
Supplier’s Catalog No IGX-44956
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:200-1:500
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Histone-lysine N-methyltransferase setd3 protein (166-265AA)
Specificity SETD3 antibody detects endogenous level of SETD3 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).