Anti-MEAF6 Antibody

Catalog No : IGX-45004
262.00€
188.00€

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Description Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A (PMID:14966270). This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription (PMID:14966270). Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4 (PMID:16387653, PMID:24065767). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (PMID:18794358).
Other names Chromatin modification-related protein MEAF6, MYST/Esa1-associated factor 6, Esa1-associated factor 6 homolog, Protein EAF6 homolog, hEAF6, Sarcoma antigen NY-SAR-91, MEAF6, C1orf149 CENP-28 EAF6
Cellular localization Kinetochore, Nucleus
Research area Epigenetics & Nuclear Signaling
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q9HAF1
Product name Anti-MEAF6 Antibody
Catalog No IGX-45004
Supplier’s Catalog No IGX-45004
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:200-1:500
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Chromatin modification-related protein MEAF6 protein (113-174AA)
Specificity MEAF6 antibody detects endogenous level of MEAF6 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).