Anti-ACE / CD143 Antibody
Catalog No : IGX-45127
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. This GPIase activity seems to be crucial for the egg-binding ability of the sperm . | ||
|---|---|---|---|
| Other names | Angiotensin-converting enzyme, ACE, EC 3.2.1.-, EC 3.4.15.1, Dipeptidyl carboxypeptidase I, Kininase II, CD antigen CD143, [Cleaved into: Angiotensin-converting enzyme, soluble form], Ace, Dcp1 | ||
| Cellular localization | Secreted, Membrane, Single-Pass Type I Membrane, Cytoplasm | ||
| Research area | Cardiovascular | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P47820 | ||
| Product name | Anti-ACE / CD143 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45127 | ||
| Supplier’s Catalog No | IGX-45127 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Rat | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:200-1:500 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Rat Angiotensin-converting enzyme protein (1046-1263AA) | ||
| Specificity | Ace antibody detects endogenous level of Ace protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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