Anti-ATP2A1 / SERCA1 Antibody
Catalog No : IGX-45184
262.00€
188.00€
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| Description | Key regulator of striated muscle performance by acting as the major Ca2+ ATPase responsible for the reuptake of cytosolic Ca2+ into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen . Contributes to calcium sequestration involved in muscular excitation/contraction (PMID:10914677). | ||
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| Other names | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, SERCA1, SR Ca,2+,-ATPase 1, EC 3.6.3.8, Calcium pump 1, Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca,2+, ATPase, ATP2A1 | ||
| Cellular localization | Endoplasmic Reticulum Membrane, Multi-Pass Membrane, Sarcoplasmic Reticulum Membrane | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | O14983 | ||
| Product name | Anti-ATP2A1 / SERCA1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45184 | ||
| Supplier’s Catalog No | IGX-45184 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:200-1:500, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 protein (384-579AA) | ||
| Specificity | ATP2A1 antibody detects endogenous level of ATP2A1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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