Anti-ABHD6 Antibody
Catalog No : IGX-45210
262.00€
188.00€
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| Description | Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol (PMID:22969151). Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways . Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids . Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism (PMID:26491015). BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting (PMID:26491015). | ||
|---|---|---|---|
| Other names | Monoacylglycerol lipase ABHD6, EC 3.1.1.23, 2-arachidonoylglycerol hydrolase, Abhydrolase domain-containing protein 6, ABHD6 | ||
| Cellular localization | Lysosome Membrane, Single-Pass Type Ii Membrane, Late Endosome Membrane, Mitochondrion Membrane | ||
| Research area | Metabolism | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9BV23 | ||
| Product name | Anti-ABHD6 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45210 | ||
| Supplier’s Catalog No | IGX-45210 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:200-1:500, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Monoacylglycerol lipase ABHD6 protein (105-211AA) | ||
| Specificity | ABHD6 antibody detects endogenous level of ABHD6 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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