Anti-KIF20B Antibody
Catalog No : IGX-45254
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Plus-end-directed motor enzyme that is required for completion of cytokinesis (PMID:11470801, PMID:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth . Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PMID:17409436). | ||
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| Other names | Kinesin-like protein KIF20B, Cancer/testis antigen 90, CT90, Kinesin family member 20B, Kinesin-related motor interacting with PIN1, M-phase phosphoprotein 1, MPP1, KIF20B, KRMP1 MPHOSPH1 | ||
| Cellular localization | Cytoskeleton, Centrosome, Spindle, Spindle Pole, Nucleus, Nucleus, Nucleolus, Nucleoplasm, Midbody, Axon, Growth Cone | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q96Q89 | ||
| Product name | Anti-KIF20B Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45254 | ||
| Supplier’s Catalog No | IGX-45254 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:200-1:500, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Kinesin-like protein KIF20B protein (1607-1731AA) | ||
| Specificity | KIF20B antibody detects endogenous level of KIF20B protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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