Anti-NEK1 Antibody
Catalog No : IGX-45298
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity (PMID:20230784). Involved in DNA damage checkpoint control and for proper DNA damage repair (PMID:20230784). In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death (PMID:20230784). May be implicated in the control of meiosis . Involved in cilium assembly (PMID:21211617). | ||
|---|---|---|---|
| Other names | Serine/threonine-protein kinase Nek1, EC 2.7.11.1, Never in mitosis A-related kinase 1, NimA-related protein kinase 1, Renal carcinoma antigen NY-REN-55, NEK1, KIAA1901 | ||
| Cellular localization | Cytoskeleton, Centrosome, Nucleus, Cytoplasm | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q96PY6 | ||
| Product name | Anti-NEK1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45298 | ||
| Supplier’s Catalog No | IGX-45298 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:200-1:500, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Serine/threonine-protein kinase Nek1 protein (626-809AA) | ||
| Specificity | NEK1 antibody detects endogenous level of NEK1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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