Anti-SOX30 Antibody
Catalog No : IGX-45323
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Acts as both a transcriptional activator and repressor (PMID:10359848, PMID:29739711). Binds to the DNA sequence 5'-ACAAT-3' and shows a preference for guanine residues surrounding this core motif (PMID:10359848). Binds to its own promoter and activates its own transcription . Required to activate the expression of postmeiotic genes involved in spermiogenesis . Binds to the promoter region of CTNNB1 and represses its transcription which leads to inhibition of Wnt signaling (PMID:29739711). Also inhibits Wnt signaling by binding to the CTNNB1 protein, preventing interaction of CTNNB1 with TCF7L2/TCF4 (PMID:29739711). | ||
|---|---|---|---|
| Other names | Transcription factor SOX-30, SOX30 | ||
| Cellular localization | Cytoplasm, Nucleus | ||
| Research area | Epigenetics & Nuclear Signaling | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | O94993 | ||
| Product name | Anti-SOX30 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45323 | ||
| Supplier’s Catalog No | IGX-45323 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:200-1:500, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Transcription factor SOX-30 protein (84-206AA) | ||
| Specificity | SOX30 antibody detects endogenous level of SOX30 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
Product Details
© 2020 Imugex All Rights Reserved