Anti-DCSTAMP Antibody
Catalog No : IGX-45324
262.00€
188.00€
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| Description | Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions. | ||
|---|---|---|---|
| Other names | Dendritic cell-specific transmembrane protein, DC-STAMP, hDC-STAMP, Dendrocyte-expressed seven transmembrane protein, IL-four-induced protein, FIND, Transmembrane 7 superfamily member 4, DCSTAMP, TM7SF4 | ||
| Cellular localization | Plasma Membrane, Membrane, Multi-Pass Membrane, Endoplasmic Reticulum Membrane, Endosome, Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9H295 | ||
| Product name | Anti-DCSTAMP Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45324 | ||
| Supplier’s Catalog No | IGX-45324 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:200-1:500, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Dendritic cell-specific transmembrane protein (119-209AA) | ||
| Specificity | DCSTAMP antibody detects endogenous level of DCSTAMP protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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