Anti-RAB21 Antibody
Catalog No : IGX-45349
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general . As a result, may regulate cell adhesion and migration . During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis (PMID:18804435). Involved in neurite growth . Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion (PMID:25648148). | ||
|---|---|---|---|
| Other names | Ras-related protein Rab-21, RAB21, KIAA0118 | ||
| Cellular localization | Golgi Apparatus, Trans-Golgi Network, Golgi Apparatus Membrane, Early Endosome Membrane, Endoplasmic Reticulum Membrane, Lipid-Anchor, Cytoplasmic Vesicle Membrane, Cleavage Furrow, Neuron Projection | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9UL25 | ||
| Product name | Anti-RAB21 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45349 | ||
| Supplier’s Catalog No | IGX-45349 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:200-1:500, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Ras-related protein Rab-21 protein (141-222AA) | ||
| Specificity | RAB21 antibody detects endogenous level of RAB21 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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