Anti-NOXO1 Antibody

Catalog No : IGX-45353
262.00€
188.00€

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Description Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. Isoform 3 is more potent than isoform 1 in activating NOX3. Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activity.
Other names NADPH oxidase organizer 1, NADPH oxidase regulatory protein, Nox organizer 1, Nox-organizing protein 1, SH3 and PX domain-containing protein 5, NOXO1, P41NOX SH3PXD5
Cellular localization Plasma Membrane, Membrane, Peripheral Membrane,
Research area Epigenetics & Nuclear Signaling
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q8NFA2
Product name Anti-NOXO1 Antibody
Catalog No IGX-45353
Supplier’s Catalog No IGX-45353
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:200-1:500, IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human NADPH oxidase organizer 1 protein (304-376AA)
Specificity NOXO1 antibody detects endogenous level of NOXO1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).