Anti-INPP5E Antibody
Catalog No : IGX-45373
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PMID:10764818) . Specific for lipid substrates, inactive towards water soluble inositol phosphates (PMID:10764818). Plays an essential role in the primary cilium by controlling ciliary growth and phosphoinositide 3-kinase (PI3K) signaling and stability . | ||
|---|---|---|---|
| Other names | 72 kDa inositol polyphosphate 5-phosphatase, EC 3.1.3.36, Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, Phosphatidylinositol polyphosphate 5-phosphatase type IV, INPP5E | ||
| Cellular localization | Membrane, Peripheral Membrane, , Golgi Stack Membrane, Cilium Axoneme, Ruffle, Cytoplasm | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9NRR6 | ||
| Product name | Anti-INPP5E Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45373 | ||
| Supplier’s Catalog No | IGX-45373 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:200-1:500, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human 72 kDa inositol polyphosphate 5-phosphatase protein (1-133AA) | ||
| Specificity | INPP5E antibody detects endogenous level of INPP5E protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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