Anti-TMEM2 Antibody
Catalog No : IGX-45392
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments (PMID:28246172). Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling . Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate (PMID:28246172). | ||
|---|---|---|---|
| Other names | Cell surface hyaluronidase, EC 3.2.1.35, Transmembrane protein 2, TMEM2, KIAA1412 | ||
| Cellular localization | Membrane, Single-Pass Type Ii Membrane | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9UHN6 | ||
| Product name | Anti-TMEM2 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45392 | ||
| Supplier’s Catalog No | IGX-45392 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:200-1:500, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Cell surface hyaluronidase protein (734-866AA) | ||
| Specificity | TMEM2 antibody detects endogenous level of TMEM2 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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