Anti-FATE1 Antibody

Catalog No : IGX-45427
262.00€
188.00€

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Description Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca2+ transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis (PMID:27402544). May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling (PMID:26567849).
Other names Fetal and adult testis-expressed transcript protein, Cancer/testis antigen 43, CT43, Tumor antigen BJ-HCC-2, FATE1, FATE
Cellular localization Endoplasmic Reticulum Membrane, Single-Pass Membrane, , Mitochondrion, Mitochondrion Outer Membrane
Research area Cancer
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q969F0
Product name Anti-FATE1 Antibody
Catalog No IGX-45427
Supplier’s Catalog No IGX-45427
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:200-1:500, IF: 1:50-1:500
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Fetal and adult testis-expressed transcript protein (1-162AA)
Specificity FATE1 antibody detects endogenous level of FATE1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).