Anti-CLPP Antibody
Catalog No : IGX-45470
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates (PMID:11923310, PMID:15522782). Cleaves PINK1 in the mitochondrion (PMID:22354088). | ||
|---|---|---|---|
| Other names | ATP-dependent Clp protease proteolytic subunit, mitochondrial, EC 3.4.21.92, Endopeptidase Clp, CLPP | ||
| Cellular localization | Mitochondrion Matrix | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q16740 | ||
| Product name | Anti-CLPP Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45470 | ||
| Supplier’s Catalog No | IGX-45470 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:500-1:1000 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human ATP-dependent Clp protease proteolytic subunit, mitochondrial protein (223-277AA) | ||
| Specificity | CLPP antibody detects endogenous level of CLPP protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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