Anti-LGMN Antibody
Catalog No : IGX-45475
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation . May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. | ||
|---|---|---|---|
| Other names | Legumain, EC 3.4.22.34, Asparaginyl endopeptidase, Protease, cysteine 1, LGMN, PRSC1 | ||
| Cellular localization | Lysosome | ||
| Research area | Immunology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q99538 | ||
| Product name | Anti-LGMN Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45475 | ||
| Supplier’s Catalog No | IGX-45475 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:500-1:1000 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Legumain protein (199-312AA) | ||
| Specificity | LGMN antibody detects endogenous level of LGMN protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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