Anti-GLRX5 Antibody

Catalog No : IGX-45490
262.00€
188.00€

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Description Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters (PMID:20364084). Involved in protein lipoylation, acting in the pathway that provides an iron-sulfur cluster to lipoate synthase (PMID:24334290). Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1 (PMID:20364084). May protect cells against apoptosis due to reactive oxygen species and oxidative stress .
Other names Glutaredoxin-related protein 5, mitochondrial, Monothiol glutaredoxin-5, GLRX5, C14orf87
Cellular localization Mitochondrion Matrix
Research area Signal Transduction
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q86SX6
Product name Anti-GLRX5 Antibody
Catalog No IGX-45490
Supplier’s Catalog No IGX-45490
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:500-1:1000
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Glutaredoxin-related protein 5, mitochondrial protein (32-157AA)
Specificity GLRX5 antibody detects endogenous level of GLRX5 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).