Anti-ESYT2 Antibody
Catalog No : IGX-45556
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS) (PMID:27044890). | ||
|---|---|---|---|
| Other names | Extended synaptotagmin-2, E-Syt2, Chr2Syt, ESYT2, FAM62B KIAA1228 | ||
| Cellular localization | Endoplasmic Reticulum Membrane, Multi-Pass Membrane, Membrane, Peripheral Membrane | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | A0FGR8 | ||
| Product name | Anti-ESYT2 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45556 | ||
| Supplier’s Catalog No | IGX-45556 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:500-1:1000, IF: 1:200-1:500 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Extended synaptotagmin-2 protein (567-736AA) | ||
| Specificity | ESYT2 antibody detects endogenous level of ESYT2 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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