Anti-RFX2 Antibody

Catalog No : IGX-45557
262.00€
188.00€

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Description Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function . Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters (PMID:10330134). Probably activates transcription of the testis-specific histone gene H1-6 .
Other names DNA-binding protein RFX2, Regulatory factor X 2, RFX2
Cellular localization Nucleus, Cytoplasm
Research area Epigenetics & Nuclear Signaling
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P48378
Product name Anti-RFX2 Antibody
Catalog No IGX-45557
Supplier’s Catalog No IGX-45557
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:500-1:1000, IF: 1:200-1:500
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human DNA-binding protein RFX2 protein (1-130AA)
Specificity RFX2 antibody detects endogenous level of RFX2 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).