Anti-FERMT1 Antibody
Catalog No : IGX-45572
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression. | ||
|---|---|---|---|
| Other names | Fermitin family homolog 1, Kindlerin, Kindlin syndrome protein, Kindlin-1, Unc-112-related protein 1, FERMT1, C20orf42 KIND1 URP1 | ||
| Cellular localization | Plasma Membrane, Ruffle Membrane, Peripheral Membrane, , Cytoskeleton, Focal Adhesion | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9BQL6 | ||
| Product name | Anti-FERMT1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45572 | ||
| Supplier’s Catalog No | IGX-45572 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:500-1:1000, IF: 1:200-1:500 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Fermitin family homolog 1 protein (321-420AA) | ||
| Specificity | FERMT1 antibody detects endogenous level of FERMT1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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