Anti-LPL Antibody
Catalog No : IGX-45575
262.00€
188.00€
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| Description | Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage (PMID:8675619, PMID:11342582, PMID:27578112). Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity (PMID:7592706, PMID:12032167). Mediates margination of triglyceride-rich lipoprotein particles in capillaries (PMID:24726386). Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (PMID:11342582, PMID:27811232). | ||
|---|---|---|---|
| Other names | Lipoprotein lipase, LPL, EC 3.1.1.34, LPL, LIPD | ||
| Cellular localization | Plasma Membrane, Membrane, Peripheral Membrane, Extracellular Side, Secreted, Extracellular Matrix | ||
| Research area | Cardiovascular | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P06858 | ||
| Product name | Anti-LPL Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45575 | ||
| Supplier’s Catalog No | IGX-45575 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:500-1:1000, IF: 1:200-1:500 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Lipoprotein lipase protein (162-246AA) | ||
| Specificity | LPL antibody detects endogenous level of LPL protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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