Anti-AMN Antibody
Catalog No : IGX-45585
262.00€
188.00€
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| Description | Membrane-bound component of the endocytic receptor formed by AMN and CUBN (PMID:14576052, PMID:30523278, PMID:29402915). Required for normal CUBN glycosylation and trafficking to the cell surface (PMID:14576052, PMID:29402915). The complex formed by AMN and CUBN is required for efficient absorption of vitamin B12 (PMID:12590260, PMID:14576052, PMID:26040326). Required for normal CUBN-mediated protein transport in the kidney (Probable). | ||
|---|---|---|---|
| Other names | Protein amnionless, AMN | ||
| Cellular localization | Plasma Membrane, Apical Membrane, Single-Pass Type I Membrane, Membrane, Endosome Membrane, Coated Pit, Secreted | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9BXJ7 | ||
| Product name | Anti-AMN Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45585 | ||
| Supplier’s Catalog No | IGX-45585 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:500-1:1000, IF: 1:200-1:500 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Protein amnionless protein (25-163AA) | ||
| Specificity | AMN antibody detects endogenous level of AMN protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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