Anti-UBR3 Antibody
Catalog No : IGX-45591
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | E3 ubiquitin-protein ligase which is a component of the N-end rule pathway . Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation . May play a role in Shh signaling by mediating the ubiquitination of Kif7 . May be important for MYH9 function in certain tissues, possibly by regulating the ubiquitination of MYH9 and consequently affecting its interaction with MYO7A (PMID:27331610). | ||
|---|---|---|---|
| Other names | E3 ubiquitin-protein ligase UBR3, EC 2.3.2.27, N-recognin-3, RING-type E3 ubiquitin transferase UBR3, Ubiquitin-protein ligase E3-alpha-3, Ubiquitin-protein ligase E3-alpha-III, Zinc finger protein 650, UBR3, KIAA2024 ZNF650 | ||
| Cellular localization | Membrane, Multi-Pass Membrane | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q6ZT12 | ||
| Product name | Anti-UBR3 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45591 | ||
| Supplier’s Catalog No | IGX-45591 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:500-1:1000, IF: 1:200-1:500 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human E3 ubiquitin-protein ligase UBR3 protein (960-1113AA) | ||
| Specificity | UBR3 antibody detects endogenous level of UBR3 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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