Anti-TMCO1 Antibody

Catalog No : IGX-45605
262.00€
188.00€

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Description Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis (PMID:27212239). In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store (PMID:27212239).
Other names Calcium load-activated calcium channel, CLAC channel, Transmembrane and coiled-coil domain-containing protein 1, Transmembrane and coiled-coil domains protein 4, Xenogeneic cross-immune protein PCIA3, TMCO1, TMCC4
Cellular localization Endoplasmic Reticulum Membrane, Multi-Pass Membrane, Golgi Apparatus Membrane
Research area Cell Biology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q9UM00
Product name Anti-TMCO1 Antibody
Catalog No IGX-45605
Supplier’s Catalog No IGX-45605
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:500-1:1000, IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Calcium load-activated calcium channel protein (43-79AA)
Specificity TMCO1 antibody detects endogenous level of TMCO1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).