Anti-MEF2A Antibody
Catalog No : IGX-45710
262.00€
188.00€
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| Description | Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter. | ||
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| Other names | Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1, MEF2A, MEF2 | ||
| Cellular localization | Nucleus | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q02078 | ||
| Product name | Anti-MEF2A Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45710 | ||
| Supplier’s Catalog No | IGX-45710 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:100-1:1000 | ||
| Molecular weight | Predicted band size: 55, 46 KDa. Observed band size: 55 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Myocyte-specific enhancer factor 2A protein (72-226AA) | ||
| Specificity | MEF2A antibody detects endogenous level of MEF2A protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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