Anti-2-hydroxyisobutyryl-Histone 1H4A (K12) Antibody
Catalog No : IGX-45744
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
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| Other names | Histone H4, HIST1H4A, H4/A, H4FA, AND, HIST1H4B, H4/I, H4FI, AND, HIST1H4C, H4/G, H4FG, AND, HIST1H4D, H4/B, H4FB, AND, HIST1H4E, H4/J, H4FJ, AND, HIST1H4F, H4/C, H4FC, AND, HIST1H4H, H4/H, H4FH, AND, HIST1H4I, H4/M, H4FM, AND, HIST1H4J, H4/E, H4FE, AND, HIST1H4K, H4/D, H4FD, AND, HIST1H4L, H4/K, H4FK, AND, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, AND, HIST2H4B, H4/O, H4FO, AND, HIST4H4 | ||
| Cellular localization | Nucleus, Chromosome | ||
| Research area | Epigenetics & Nuclear Signaling | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P62805 | ||
| Product name | Anti-2-hydroxyisobutyryl-Histone 1H4A (K12) Antibody | ||
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| Catalog No | IGX-45744 | ||
| Supplier’s Catalog No | IGX-45744 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, WB, ICC, IF, IP, ChIP | ||
| Recommended dilutions | WB: 1:100-1:1000, ICC: 1:20-1:200, IF: 1:10-1:100, IP: 1:200-1:2000 | ||
| Molecular weight | Predicted band size: 12 KDa. Observed band size: 12 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Peptide sequence around site of 2-hydroxyisobutyryl-Lys (12) derived from human Histone H4 | ||
| Specificity | 2-Hydroxyisobutyryl-HIST1H4A (K12) antibody detects endogenous level of 2-Hydroxyisobutyryl-HIST1H4A (K12) protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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