Anti-Cd74 Antibody
Catalog No : IGX-45915
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. Class-II-associated invariant chain peptide: Binds to the peptide-binding site of MHC class II alpha/beta heterodimers forming an alpha-beta-CLIP complex, thereby preventing the loading of antigenic peptides to the MHC class II complex until its release by HLA-DM in the endosome. | ||
|---|---|---|---|
| Other names | H-2 class II histocompatibility antigen gamma chain, Ia antigen-associated invariant chain, Ii, MHC class II-associated invariant chain, CD antigen CD74, Cd74 | ||
| Cellular localization | Membrane, Single-Pass Type Ii Membrane | ||
| Research area | Immunology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P10247 | ||
| Product name | Anti-Cd74 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45915 | ||
| Supplier’s Catalog No | IGX-45915 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Rat, Mouse | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:1000-1:5000 | ||
| Molecular weight | Predicted band size: 32 KDa. Observed band size: 32 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Rat H-2 class II histocompatibility antigen gamma chain protein (57-280AA) | ||
| Specificity | Cd74 antibody detects endogenous level of Cd74 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
Product Details
© 2020 Imugex All Rights Reserved