Anti-Fcmr Antibody
Catalog No : IGX-45936
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation . | ||
|---|---|---|---|
| Other names | Fas apoptotic inhibitory molecule 3, IgM Fc fragment receptor, Regulator of Fas-induced apoptosis Toso, Fcmr, Faim3 Toso | ||
| Cellular localization | Membrane, Single-Pass Membrane | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | A1KXC4 | ||
| Product name | Anti-Fcmr Antibody | ||
|---|---|---|---|
| Catalog No | IGX-45936 | ||
| Supplier’s Catalog No | IGX-45936 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Mouse, Rat | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:1000-1:5000 | ||
| Molecular weight | Predicted band size: 48 KDa. Observed band size: 48 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Mouse Fas apoptotic inhibitory molecule 3 protein (18-262AA) | ||
| Specificity | Fcmr antibody detects endogenous level of Fcmr protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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