Anti-PFN1 Antibody
Catalog No : IGX-46029
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR. | ||
|---|---|---|---|
| Other names | Profilin-1, Epididymis tissue protein Li 184a, Profilin I, PFN1 | ||
| Cellular localization | Cytoskeleton | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P07737 | ||
| Product name | Anti-PFN1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-46029 | ||
| Supplier’s Catalog No | IGX-46029 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:1000-1:5000 | ||
| Molecular weight | Predicted band size: 16 KDa. Observed band size: 16 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Profilin-1 protein (2-140AA) | ||
| Specificity | PFN1 antibody detects endogenous level of PFN1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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