Anti-B2M / Beta-2-microglobulin Antibody
Catalog No : IGX-46036
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PMID:25356553). | ||
|---|---|---|---|
| Other names | Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3], B2M | ||
| Cellular localization | Secreted, Cell Surface | ||
| Research area | Cardiovascular | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P61769 | ||
| Product name | Anti-B2M / Beta-2-microglobulin Antibody | ||
|---|---|---|---|
| Catalog No | IGX-46036 | ||
| Supplier’s Catalog No | IGX-46036 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:1000-1:5000 | ||
| Molecular weight | Predicted band size: 14 KDa. Observed band size: 14 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Beta-2-microglobulin protein (22-119AA) | ||
| Specificity | B2M antibody detects endogenous level of B2M protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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