Anti-ptxA Antibody
Catalog No : IGX-46095
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD+ into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors. | ||
|---|---|---|---|
| Other names | Pertussis toxin subunit 1, PTX S1, Islet-activating protein S1, IAP S1, NAD-dependent ADP-ribosyltransferase, EC 2.4.2.-, ptxA | ||
| Cellular localization | Secreted | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P04977 | ||
| Product name | Anti-ptxA Antibody | ||
|---|---|---|---|
| Catalog No | IGX-46095 | ||
| Supplier’s Catalog No | IGX-46095 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Bordetella pertussis | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:1000-1:5000 | ||
| Molecular weight | Predicted band size: 36 KDa. Observed band size: 36 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Bordetella pertussis Pertussis toxin subunit 1 protein (35-269AA) | ||
| Specificity | ptxA antibody detects endogenous level of ptxA protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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