Anti-RAB32 Antibody
Catalog No : IGX-46108
262.00€
188.00€
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| Description | Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission (PMID:12186851). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (PMID:21255211). Plays an important role in the control of melanin production and melanosome biogenesis (PMID:23084991). In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes . | ||
|---|---|---|---|
| Other names | Ras-related protein Rab-32, RAB32 | ||
| Cellular localization | Mitochondrion, Mitochondrion Outer Membrane, Lipid-Anchor, Phagosome, Phagosome Membrane, , Melanosome, Melanosome Membrane | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q13637 | ||
| Product name | Anti-RAB32 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-46108 | ||
| Supplier’s Catalog No | IGX-46108 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:1000-1:5000 | ||
| Molecular weight | Predicted band size: 25 KDa. Observed band size: 25 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Ras-related protein Rab-32 protein (2-225AA) | ||
| Specificity | RAB32 antibody detects endogenous level of RAB32 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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