Anti-PYHIN1 Antibody
Catalog No : IGX-46128
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Major mediator of the tumor suppressor activity of IFN in breast cancer cells. Promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization. Promotes ubiquitination and subsequent degradation of HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells. | ||
|---|---|---|---|
| Other names | Pyrin and HIN domain-containing protein 1, Interferon-inducible protein X, PYHIN1, IFIX | ||
| Cellular localization | Nucleus, Nucleus Speckle | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q6K0P9 | ||
| Product name | Anti-PYHIN1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-46128 | ||
| Supplier’s Catalog No | IGX-46128 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:1000-1:5000 | ||
| Molecular weight | Predicted band size: 56, 21 KDa. Observed band size: 56, 22, 84 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Pyrin and HIN domain-containing protein 1 protein (1-245AA) | ||
| Specificity | PYHIN1 antibody detects endogenous level of PYHIN1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
Product Details
© 2020 Imugex All Rights Reserved