Anti-HSD17B11 Antibody
Catalog No : IGX-46164
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. | ||
|---|---|---|---|
| Other names | Estradiol 17-beta-dehydrogenase 11, EC 1.1.1.62, 17-beta-hydroxysteroid dehydrogenase 11, 17-beta-HSD 11, 17bHSD11, 17betaHSD11, 17-beta-hydroxysteroid dehydrogenase XI, 17-beta-HSD XI, 17betaHSDXI, Cutaneous T-cell lymphoma-associated antigen HD-CL-03, CTCL-associated antigen HD-CL-03, Dehydrogenase/reductase SDR family member 8, Retinal short-chain dehydrogenase/reductase 2, retSDR2, Short chain dehydrogenase/reductase family 16C member 2, HSD17B11, DHRS8 PAN1B SDR16C2 | ||
| Cellular localization | Endoplasmic Reticulum, Lipid Droplet | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q8NBQ5 | ||
| Product name | Anti-HSD17B11 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-46164 | ||
| Supplier’s Catalog No | IGX-46164 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:1000-1:5000 | ||
| Molecular weight | Predicted band size: 33 KDa. Observed band size: 33 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Estradiol 17-beta-dehydrogenase 11 protein (20-300AA) | ||
| Specificity | HSD17B11 antibody detects endogenous level of HSD17B11 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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