Anti-RMI1 Antibody
Catalog No : IGX-46183
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability. | ||
|---|---|---|---|
| Other names | RecQ-mediated genome instability protein 1, BLM-associated protein of 75 kDa, BLAP75, FAAP75, RMI1, C9orf76 | ||
| Cellular localization | Nucleus | ||
| Research area | Epigenetics & Nuclear Signaling | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9H9A7 | ||
| Product name | Anti-RMI1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-46183 | ||
| Supplier’s Catalog No | IGX-46183 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:1000-1:5000 | ||
| Molecular weight | Predicted band size: 70 KDa. Observed band size: 70 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human RecQ-mediated genome instability protein 1 protein (181-443AA) | ||
| Specificity | RMI1 antibody detects endogenous level of RMI1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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